Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep961 | Thyroid | ECE2023

Alemtuzumab-Induced Autoimmune Thyroid Dysfunction. A review of two cases

Lois Chicharro Pablo , Miren Azcutia Uribe Echevarria Ane , Ferreira-Ocampo Pablo , Carolina Doejo Marciales Sandra , Fabiola Barra Malig Solange , Edward Astunague Condori Remy , Almodovar Ruiz Francisca

Introduction: Alemtuzumab is an humanized monoclonal antibody used for treatment of Relapsing remitting Multiple Sclerosis (RRMS). One of its main adverse effects is thyroid dysfunction, being a fluctuating hypothyroidism the most frequent presentation. Sometimes this thyroid disturbance is so significant that it might lead to alemtuzumab withdrawal. We present two Clinical cases of hyperthyroidism secondary to alemtuzumab with different clinical courses. <p class="abstext...